Large study provides new insights in autism’s genetic code

Thursday, February 22, 2007

In the largest study of its kind, a genetic analysis of 1,168 families with multiple cases of autism has identified genetic links to autism. A previously overlooked stretch of DNA on chromosome 11 implicates a gene called neurexin 1 and increases the evidence for the involvement of neurexins and genes related to glutamate transmission in the brain.

Genetic studies of autism have previously been undertaken; however the new study involves the collaboration of more than 120 scientists from more than 50 institutions representing 19 countries who pooled their data as part of the Autism Genome Project. The findings were published in the Feb. 18 issue of Nature Genetics.

Bob Wright, co-founder of Autism Speaks, a non-profit organization dedicated to increasing awareness of autism, said: “The identification of susceptibility genes will provide profound new insight into the basis of autism offering a route to breakthroughs in new treatments in support of families.” Autism Speaks funded this project in conjunction with the U.S. National Institutes of Health.

Joachim Hallmayer, MD, associate professor of psychiatry at Stanford and chair of the collaboration’s executive committee, explains what is next: “While promising, these results need to be followed up with more refined genetic maps to home in on other specific candidate genes. We also need to look more closely at chromosomal anomalies in large samples of children with autism.” In the paper, researchers caution that the genetic foundation of autism probably involves multiple genes and chromosomal abnormalities.

Autism affects about one in every 150 children, and the CDC has called it an “urgent health concern”. Autism is a developmental disorder which impairs social interaction, communication and features restricted and repetitive interests and activities. Twin studies and other research clearly suggest a genetic basis for the condition. Currently there is no cure for autism, but both behavioral or sensory interventions and drugs can influence the symptoms.

Retrieved from “https://en.wikinews.org/w/index.php?title=Large_study_provides_new_insights_in_autism%27s_genetic_code&oldid=1982993”

Glasgow cannabis enthusiasts celebrate ‘green’ on city green

Tuesday, April 22, 2014

Coinciding with Easter Sunday, Glasgow Cannabis Social Club’s annual 420 event was held on Glasgow Green, under sunny blue skies, and overlooking the river Clyde. Despite the city’s council attempting to revoke permission for the gathering at the last minute, police were happy for it to go-ahead with approximately a dozen officers attending in high-visibility vests.

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The Daily Record reported five arrests were made for minor offences, likely smoking and possession of small quantities of cannabis. Taking a less-sensational — and more accurate — line of reporting, the Monday edition of Glasgow’s Evening News stated five were referred to the Procurator Fiscal who is responsible for deciding if charges should be brought.

Official figures provided by the police were that 150 attended. With people coming and going, Wikinews reporters estimated upwards of 200 attended, compared to nearly 700 who had signed up for the event on Facebook. Hemp goods were advertised and on sale at the event, and some attendees were seen drinking cannabis-themed energy drinks.

“I was searched and charged under the Misuse of Drugs Act (which is a lot of bollocks)” one attendee noted online, adding “not fair to happen on a brilliant day like it was, other than that I had a great day!” A second said they were openly smoking and ignored by police, who “were only really focusing on people who looked particularly young”.

Cannabis seeds were openly and legally sold at the event and a hydroponics supplier brought a motortrike towing an advertising trailer. Actually growing cannabis is, however, illegal in the UK.

With the event openly advocating the legalisation of cannabis, speakers put their arguments for this to a receptive crowd. Retired police officer James Duffy, of Law Enforcement Against Prohibition, spoke of the failed United States alcohol prohibition policy; stressing such policies needlessly bring people into contact with criminal elements. Highlighting other countries where legalisation has been implemented, he pointed out such led to lower crime, and lower drug use overall.

One speaker, who produced a bottle of cannabis oil he had received through the post, asserted this cured his prostate cancer. Others highlighted the current use of Sativex by the National Health Service, with a cost in-excess of £150 for a single bottle of GW Pharmaceuticals patented spray — as-compared to the oil shown to the crowd, with a manufacturing cost of approximately £10.

Similar ‘420’ pro-cannabis events were held globally.

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Hiring A Licensed Electrician: Pros &Amp; Cons

An electrician is an electrical contractor that you hire for remodeling jobs or new construction. These professionals can be licensed or not. Many homeowners wonder if it’s really necessary to hire the fully licensed company or individual when there are cheaper ways to get the jobs done.Electricians run new wires or replace old ones. They handle electrical boxes, fuses, conduit and circuits. They follow blueprints and plans designed by electrical engineers in order to create working systems within a home or commercial building. Some handymen and jacks-of-all-trades claim to be able to fix your wiring, but buyer beware: electric installations or repairs are complicated endeavors that demand respect from DIYers. Faulty wiring can be disastrous. Here are some pros and cons for hiring a licensed vs. unlicensed individual or business.Pros of Hiring a Licensed Electrician:- Licensed pros have had to do coursework in order to learn the ins and outs of electricity. Not only did they have to study and pass tests, they also had to spend time working out in the field acquiring hands-on experience.- A homeowner can check with the local board of electrical contractors in order to learn about a pro’s past history. Is his or her license up to date? Have there been any unresolved complaints about them? These are important items to check into.- Building codes are set up to ensure public safety, and licensed contractors will stay up to date with them. When electrical work is done, the local municipalities will inspect it to make sure it’s done correctly.- In order to go through the steps to get their license, these individuals had to be dedicated to their craft and in refining their skill set. This dedication will shine through in the degree to which you can trust their work.Pros of Hiring an Unlicensed Electrician:- An unlicensed person’s fees will be less expensive than one licensed. If you “know a guy” who can do the work you need done, and if it’s not a huge task, you might be able to save some money here.- Since an unlicensed worker won’t usually bother with permits and inspections, the job will be completed faster, which is cool if you’re trying to finish the work in a hurry.Cons of a Licensed Professional:- It will cost more cash to hire a professional, but it’s important to remember that you often get what you pay for.- A homeowner will have to get permits and wait for inspectors. Still, the homeowner will be assured that when all is done, the job has been done right.Cons of an Unlicensed Handyman:- Crossed wires can short out and burn your house down. Worse yet, if the insurance company learns that a non-professional performed the work, they may not pay for the damage caused by the fire.- Because the handyman isn’t being watched over by municipalities, inspectors or the board of contractors, if something goes wrong, there’s no recourse.When building a new house or remodeling, there are many decisions to be made. Deciding between hiring an unlicensed or licensed electrician is one of them. After weighing the facts, a homeowner will have to make a decision for him or herself.

No survivors in Cambodian air crash

Wednesday, June 27, 2007

No survivors were found today when searchers reached the crash site of PMTair Flight U4 241 in Cambodia, a government minister said.

“All have died. It is confirmed,” Information Minister Khieu Kanharith told reporters.

The wreckage of the PMTair Antonov An-24 was spotted by a helicopter crew early this morning, two days after the plane went missing from radar screens while on a flight from Angkor International Airport in Siem Reap to the beach-resort town of Sihanoukville.

The crash site is located in the Dâmrei Mountains, or Elephant Mountains, northeast of Bokor Hill Station in Kampot Province, about 150 kilometers south of Phnom Penh, the capital.

Rescue helicopter pilot Tep Sitha, speaking to Reuters by mobile telephone, described the crash site as “high on the mountain.”

A search operation involving around 1,000 people had scoured the mountainous jungle territory since the plane crashed on Monday. Monsoon rains, thick jungle and rugged terrain had hampered the search.

The 44-seat plane had 22 people aboard – 16 passengers, plus a flight crew of six – a Russian pilot, two Cambodian co-pilots, a Cambodian flight engineer and two Cambodian flight attendants. Among the passengers, 13 were from South Korea and three were from the Czech Republic.

Around a dozen Korean family members arrived in Phnom Penh yesterday from Seoul, and the Cambodian government said it would pay for their accommodations.

The cause of the crash is yet to be determined by an examination of the flight data recorder, but officials had earlier speculated that weather may have played a part.

The airline, PMTair, is a small Cambodian carrier that listed its fleet at five planes, including two Antonov An-24s, which it used for domestic flights. The type of Soviet-built plane, introduced in 1963, is common in Cambodia’s civil and military aviation fleet.

Sar Sareth, director of PMTair, told the Associated Press yesterday that he did not know what year the crashed plane was built. He said it was in “good condition” before taking off, and “was always in compliance with flight technical and safety procedures.”

The airline had begun regularly scheduled Siem Reap-Sihanoukville flights in January, providing a direct link between the two popular tourist towns.

In addition to domestic service, PMTair has international routes, including direct flights from Seoul to Siem Reap, feeding a large influx of tourists from South Korea in the past few years. Last year, around 250,000 South Koreans visited the country.

Yesterday, a South Korean government agency said it was putting PMTair on a list of carriers it was checking for safety. “As PMT also does business at Incheon International Airport, a special safety inspection for the airline will be carried out until July 6,” Chung Sang-ho, head of the Civil Aviation Safety Authority, was quoted as saying by Yonhap News Agency.

One other Cambodian carrier, Royal Khmer Airlines, was also on the South Korean list, as was Garuda Indonesia, and three Russian carriers, SAT Airlines, Vladivostok Air and Dalavia.

Before Monday’s crash, the worst incident for PMTair was a hard landing in 2005, when a piece of landing gear snapped off an An-24 on landing at Banlung, Ratanakiri, overcrowded with 59 passengers aboard. There were no injuries, but the airline was temporarily grounded after the incident. In another incident, a plane had to return to the airport after takeoff because of engine failure.

The crash is Cambodia’s first major aviation accident in nearly 10 years. In September 1997, a Vietnam Airlines Tupolev Tu-134 crashed while trying to land in heavy rain at Phnom Penh International Airport, killing 65 people and one person, a toddler, surviving.

Retrieved from “https://en.wikinews.org/w/index.php?title=No_survivors_in_Cambodian_air_crash&oldid=3130987”

Nokia appoints Microsoft Business Division Head as chief executive

Sunday, September 12, 2010

The Finnish communications corporation Nokia announced that its Head will change on September 21. The previous chief executive Olli-Pekka Kallasvuo will continue to chair in non-executive capacity. The head of Microsoft Business division Stephen Elop will take the position. It is the first time a non-Finn becomes Nokia president and chief executive.

The change follows Nokia’s fall in world markets. It includes a decrease in Nokia’s American market share to less than ten percent after failed negotiations with a number of leading American phone providers. An analyst at a market analyst company Canalys, Pete Cunningham, said, “Despite holding 38 percent market share of the smartphone market, Nokia’s failure to compete with the iPhone and high-tier Android devices, combined with its lack of progress in gaining significant traction in the United States, has led to press and investor dissatisfaction.”

Some commenters suggested that Nokia chose Mr. Elop partly because he is a Canadian, following criticism of American candidates by the Finnish press. However a Nokia spokesman rejected this, saying, “Nationality was not a selection criteria.”

Stephen Elop was president and CEO of the graphics and web-development software house Macromedia prior to its acquisition by Adobe in 2005. He then joined Microsoft as President of Microsoft’s Business Division in January, 2008. Commenting on his new role he said, “Nokia has a unique global position as well as a great brand upon which we can build. The Nokia slogan clearly states our key mission: Connecting People, which will acquire new dimensions as we build our portfolio of products, solutions and services.”

In the announcement the Chairman of the Nokia Board of Directors Jorma Ollila stressed an expected shift of focus from hardware to software. “His [Stephen Elop’s] strong software background and proven record in change management will be valuable assets as we press harder to complete the transformation of the company. We believe that Stephen will be able to drive both innovation and efficient execution of the company strategy in order to deliver increased value to our shareholders”.

Nokia stated in an official blog post, “Nokia is transitioning from a hardware manufacturer of mobile devices to a software and solutions business. …Stephen’s background in the software industry is one of his key strengths.”

Retrieved from “https://en.wikinews.org/w/index.php?title=Nokia_appoints_Microsoft_Business_Division_Head_as_chief_executive&oldid=4500263”

Flexiski’s Corporate Ski Breaks}

Flexiski’s corporate ski breaks

by

Louise Aldridge

Flexiski have been organising corporate ski trips for high profile clients including Goldman Sachs, Credit Suisse, Volvo and Nokia to the top ski resorts in Europe for the last 20 years. Their new 2011/12 ski brochure focuses more on the choice of venues and facilities that can be provided for corporate ski events. A corporate ski break is an ideal way of entertaining clients, team-building or rewarding a companys best employees and selecting the right venue and facilities is paramount to making the trip a success.

The Hotel Saint Louis in Courchevel 1850 is one of flexiskis featured properties, suitable for a corporate ski event. Whether you are looking to arrange a large conference or simply need to host an intimate meeting, this multi-functional venue offers complete flexibility and the capability to deliver your desired corporate event. White-label branding options are also available in the hotel which enables a company to make their trip more bespoke.

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Up until the end of August 2011, groups will be able to benefit from special savings at the Hotel Saint Louis, with 1 in 12 guests staying for free. Half price ski equipment hire will also be available with Sunday to Wednesday stays at the hotel which start from 410pp.* And, as you may not have your own private office to organise every element of your holiday let their event management service do it for you. The Flexigold service provides a UK-based personal Travel Consultant dedicated to plan your requirements for the trip, and also includes your own Ski Event Manager in the resort think of having a personal assistant, expert skier and events manager there with you. The Ski Event Manager will organise and supervise everything you want: from a hot air balloon ride, to building an igloo or wine tasting and even jumping queues for a nightclub!

Flexiski will also be hosting some key events throughout the season at the Hotel Saint Louis in Courchevel 1850 ranging from the pre-Christmas party to the end-of-season Easter weekend with BBQ and Pimms on La Terrasse. These are back by popular demand following great success last season!

For more information on corporate ski breaks call flexiski on 020 8939 0864 or visit www.flexiski.com.

*Book before 31st August 2011

Flexiski

specialise in tailor-made ski breaks for individuals, families and corporate groups to 16 of the most prestigious

ski resorts

in Europe. Whether you are looking for a long weekend, a mid-week break or more traditional 7 night holiday, flexiski can create your perfect ski holiday. Contact flexiski on 020 8939 0864 or visit www.flexiski.com

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Flexiski’s corporate ski breaks}

British Prime Minister David Cameron makes unannounced visit to Libya

Friday, February 1, 2013

British Prime Minister David Cameron made an unannounced visit to the Libyan capital city of Tripoli yesterday after visiting Algeria earlier in the day.

David Cameron pledged that Britain would help in training Libya’s security forces. He said in a joint press conference held with Libyan Prime Minister Ali Zeidan that “the British people want to stand with you and help you deliver the greater security that Libya needs”. Cameron also reiterated his support for the French-backed intervention in Mali, denying suggestions put to him that foreign intervention in Islamic countries would lead to a backlash against Western nations by al-Qaeda.

The security was tight during his walkabout in the Martyrs’ Square, where police attempted to hold back the locals as a police helicopter flew overhead. His visit to Tripoli comes in the aftermath of recent threats to the British embassy and just a week after British citizens were urged to leave the second largest city of Benghazi due to a “specific and imminent” threat to Westerners.

Police officers investigating the 1988 Lockerbie bombing from the Dumfries and Galloway Constabulary have been granted access to new information to help them with their inquiries. In 2001, Abdelbaset al-Megrahi was convicted of murder and sentenced to life imprisonment but was released in 2009 on compassionate health grounds and died last year.

Retrieved from “https://en.wikinews.org/w/index.php?title=British_Prime_Minister_David_Cameron_makes_unannounced_visit_to_Libya&oldid=4590889”

Wikinews interviews Democratic candidate for the Texas 6th congressional district special election Daryl Eddings, Sr’s campaign manager

Tuesday, April 20, 2021

Wikinews extended invitations by e-mail on March 23 to multiple candidates running in the Texas’ 6th congressional district special election of May 1 to fill a vacancy left upon the death of Republican congressman Ron Wright. Of them, the office of Democrat Daryl Eddings, Sr. agreed to answer some questions by phone March 30 about their campaigns and policies. The following is the interview with Ms Chatham on behalf of Mr Eddings, Sr.

Eddings is a federal law enforcement officer and senior non-commissioned officer in the US military. His experience as operations officer of an aviation unit in the California National Guard includes working in Los Angeles to control riots sparked by the O. J. Simpson murder case and the police handling of Rodney King, working with drug interdiction teams in Panama and Central America and fighting in the Middle East. He is the founder of Operation Battle Buddy, which has under his leadership kept in touch with over 20 thousand veterans and their families. He was born in California, but moved to Midlothian, Texas. He endeavours to bring “good government, not no government”. Campaign manager Faith Chatham spoke to Wikinews on matters ranging from healthcare to housing.

An Inside Elections poll published on March 18 shows Republican candidate Susan Wright, the widow of Ron Wright, is ahead by 21% followed by Democrat Jana Sanchez with 17% and Republican Jake Ellzey with 8% with a 4.6% margin of error among 450 likely voters. The district is considered “lean Republican” by Inside Elections and voted 51% in favour of Donald Trump in last year’s US presidential election. This is down from 54% for Trump in 2016’s presidential election, the same poll stated.

Retrieved from “https://en.wikinews.org/w/index.php?title=Wikinews_interviews_Democratic_candidate_for_the_Texas_6th_congressional_district_special_election_Daryl_Eddings,_Sr%27s_campaign_manager&oldid=4684113”

Grand National winning horse ‘Comply or Die’ dies, aged 17

Wednesday, May 11, 2016

Comply or Die, the racehorse who won the 2008 Grand National has died at the age of 17. His death was announced by his former trainer, David Pipe. He died over at the weekend in Gloucestershire, where he had been staying with jockey Timmy Murphy. He was cremated on Monday and his ashes will return to Murphy.

Murphy was the jockey in the saddle when Comply or Die won the 2008 Grand National. Speaking to the Press Association, he spoke about the horse’s death. He said, “He was part of the furniture at home so it’s very sad. He gave me the greatest day of my career, obviously that can never be taken away. He paraded at Cheltenham and Aintree and was getting ready to do some dressage in the summer. I’m not actually sure how he died, to be honest, but it wasn’t nice to come home to. He was cremated on Monday. He was a happy horse and he was also very clever.”

During his racing career he made £798,809 in prize-money after winning a total of eight races.

The 2008 Grand National victory was his greatest achievement and he almost matched it when he came second place in 2009. He retired in 2011 but remained active, often being paraded at race grounds such as Aintree and Cheltenham. He also participated in some hunting activities. Pipe said, “Since his retirement he had been a lead-horse at Timmy Murphy’s establishment before trying his hand at dressage, a discipline in which he had proven very successful”.

Tributes have been paid to Comply or Die on social media by horse racing fans with several tweeting their appreciation and memories.

Retrieved from “https://en.wikinews.org/w/index.php?title=Grand_National_winning_horse_%27Comply_or_Die%27_dies,_aged_17&oldid=4216560”

Most Psychic Readers Use Astrology To Help Assist Them With Their Gifts.}

Submitted by: Wilson Comley

This time in the calendar year everyoneinquires about upcoming associations, occupation and financial potentials for 2004. What in regards to the important planetary aspects and occasions taking area within the year? Bring benefit from the following to program your twelve months forward. Most psychic readers use astrology to help assist them with their gifts.

Through the period of time of May possibly 17-June 29, 2004 Venus enters Retrograde. Venus will be the planet of love, reflecting and revisingthe loving principal is essential. Affection is stagnant and inwardly expressed. This will not be a time to start dating or get married. If you might be spending for an high pricedmatchmaking or courting program, this would be an ideally suited time to freeze your membership.On the other hand, it can be an fantastic time to review and refresha existing partnership.

Due to the fact Venus policies money, logically revenue is earned by way of give good results. Throughout the Venus Retrograde of October by way ofNovember 2002,a building supervisor was hired to handle a developing in alternate for the cost-free condominium. This supervisor not only embarked on a brand new work, but also a new home.She detested the employment and hated her located problems. She quit prior to Venus turned immediate. In significantly less than six weeks, she moved twice. I wonder regarding the 3rd area she moved to promptly thereafter. It can be advised to place on carry any key actions, conclusions or embarking any new ventures on this retrograde.

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From a give good results standpoint, HARDLY EVER EVER START A BRAND NEW POSITION WHATSOEVER WITH A VENUS RETROGRADE! The task will not be liked as well as a far better job generally turns into available after the retrograde. The amount of appreciation is unexpressed plus the job duties may not be liked. Worse, they may not have been stated directly from the beginning.

Since Venus principles elegance, plastic surgical procedure is just not recommended. Throughout the Venus Retrograde of January 1989 a consumer underwent Rhinoplasty (Nose Task). Though she did like her doctor, she didn’t just like the final results. She obtained her nose redone. Also, yet another client, a nurse,assisted inside operating room when a specific male singer underwent Rhinoplasty and 2 other procedures.This performer is notorious for getting an excessive amount of plastic surgical treatment for the level ofoverboard. Upon checking the day, it as well landed over a Venus retrograde. However, it undoubtedly justify why this particular person has and almost certainly will continually go under the knife multiple occasions. .

Venus’ pleasure principal is just not at its fullest. Interpersonal functions are comprehensive “busts” using a retrograde. By no means strategy a important social gathering because bothno one exhibits or even the celebration is boring! Worse, vacations are usually not advised. During Venus retrograde April 1912a cruise was not fulfilling. THE TITANIC SANK! Granted, there were difficult facets fromVenus retrograde to Neptune (the sea). But for those people that took a vacation, they didn’t fine enjoyment or get their money’s really worth. Interestingly,the videowas released a few weeks earlier than Venus went retrograde. The film was about a VenusRetrograde affair that made the film much more well-known using a Venus Retrograde throughout late December 1997 through early January 1998. At some position do not be shocked if it’s re-released.

With a constructive word, please don’t forget the above isto strengthen greater periods to assert actions. Absolutely nothing is a catastrophe. Help save your money and time. Tend not to make any main conclusions or commit time in seeking to tackle a major affair that you’ll be able to placed away from till the time is superior. Even so, do use this time period to evaluate your patterns in everyday life. It can be an excellent strategy to mature as someone. Expansion does bring about attainment!

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